🩺 Fractional Chief Medical Officer

Your Fractional Chief Medical Officer — Senior Clinical Leadership Without the Full-Time Hire

The clinical expertise of a Chief Medical Officer, available 1–2 days per week. Governance, regulatory affairs, patient safety, and medical strategy — for the organisations that need it most but can't yet justify a full-time appointment.

20+
Years Clinical & Industry Experience
13
Service Domains
1–2
Days per Week
6mo+
Minimum Engagement

Areas of Expertise

Clinical Governance Patient Safety Regulatory Affairs Medical Strategy MHRA / NICE CQC Readiness Medical Affairs PSIRF Clinical Research Digital Health Pharmacovigilance AI Governance

Currently accepting new engagements — next availability: May 2026

Fractional Chief Medical Officer Services for Growing Healthcare Organisations

The fractional CMO model is ideal where clinical leadership is absent or under-resourced. If you have one medic or none and need senior clinical input, this is designed for you.

🚀

Digital Health & HealthTech

Start-ups and scale-ups needing clinical credibility — for investors, DCB0129/DTAC compliance, and building trust with NHS buyers.

🔬

MedTech & Diagnostics SMEs

Device companies working towards UKCA/CE marking that need a clinical evaluation lead, post-market surveillance, and regulatory strategy.

🧪

Early-Stage Biotech & Pharma

Pre-Series A to Series B companies needing their first medical affairs function, pharmacovigilance, or clinical trial oversight.

🏥

Private Clinic Groups

Independent GP networks, aesthetics groups, cosmetic surgery chains, and specialist clinics that need CQC governance and a named medical lead.

🏠

Care & Homecare Providers

Care home groups, homecare organisations, and supported living providers regulated by CQC that lack an in-house medical director.

💼

Corporate & Occupational Health

Employers and occupational health providers building a structured health and wellbeing programme needing senior clinical oversight.

🛒

Consumer Health & Nutrition

Supplement brands, functional food companies, and wellness products needing medical affairs and health claims substantiation.

🏃

Sports, Aesthetics & Lifestyle Medicine

Sports medicine clinics, elite performance centres, and aesthetic medicine groups requiring clinical governance and medical director-level oversight.

⚖️

Health Insurance & Medico-Legal

Insurtech and health insurance products needing clinical governance, and legal practices requiring a senior clinical expert witness or medical advisor.

Why Hire a Fractional CMO? Thirteen Areas of Clinical Leadership

A fractional Chief Medical Officer delivers the full breadth of a CMO function — governance, regulatory, safety, strategy — at a scale and cost appropriate to your organisation's stage.

01

Clinical Governance & CQC Readiness

Build and embed a clinical governance framework — from policy architecture and clinical audit to serious incident review. Prepare your organisation for CQC inspection and ensure you are operating safely and compliantly.

CQCGovernanceClinical AuditPSIRF
02

Regulatory Affairs — MHRA, NICE & UKCA

Navigate the UK regulatory landscape with confidence. Develop your MHRA submission strategy, manage clinical evaluation reports for UKCA/CE marking, or prepare for a NICE submission or health technology assessment.

MHRANICEUKCACE Marking
03

Patient Safety & Pharmacovigilance

Design and implement a robust patient safety framework, including Duty of Candour, serious incident reporting under PSIRF, and pharmacovigilance systems for drug and device companies.

PSIRFPharmacovigilancePatient Safety
04

Medical Affairs Strategy

Build the medical affairs function your organisation needs — publications strategy, KOL engagement, medical education, scientific advisory boards, and evidence generation planning.

Medical AffairsPublicationsKOL
05

Digital Health — DCB0129 & DTAC

Act as Clinical Safety Officer under DCB0129, lead the Digital Technology Assessment Criteria (DTAC) process, and provide clinical oversight for AI/ML-enabled digital health products seeking NHS adoption.

DCB0129DTACClinical SafetyAI Governance
06

Investor & Fundraising Clinical Support

Provide clinical credibility for investor presentations, due diligence processes, and funding applications. Experienced supporting Series A–C rounds, NHS procurement bids, and grant applications.

Due DiligenceInvestor ReadinessSeries A–C
07

Clinical Research & Evidence Strategy

Design clinical evaluation strategies, oversee evidence generation programmes, advise on study design and site selection, and manage CRO relationships for early-phase and observational research.

Clinical TrialsEvidence StrategyCRO Management
08

Named Medical Director / Responsible Person

Act as the named Medical Director, Responsible Officer, or Designated Prescribing Practitioner as required by CQC, NHS England, or your regulator — providing the clinical leadership sign-off your registration requires.

Named Medical DirectorResponsible OfficerCQC
09

Medico-Legal & Expert Witness

Provide senior clinical expert opinion in medico-legal contexts — from initial case review and opinion letters through to CPR Part 35-compliant expert reports and occasional court attendance.

Expert WitnessCPR Part 35Medico-Legal

Four Steps to Your Fractional Chief Medical Officer

From first contact to a working fractional CMO engagement typically takes 10–14 days.

1

Discovery Call

A 30-minute confidential call to understand your organisation, your clinical risks, and what you need from senior medical leadership.

2

Scope & Proposal

A clear written proposal — engagement level, working rhythm, deliverables, and transparent pricing — returned within 48 hours of the discovery call.

3

Agreement & Onboarding

Contracts signed digitally. Structured onboarding session with your leadership team, followed by an initial clinical risk and governance assessment.

4

Ongoing Engagement

Regular working sessions, board attendance, async availability, and quarterly reviews. Real clinical leadership, not just advice on paper.

Fractional CMO Engagement Options

Three engagement levels matched to the complexity and scale of your clinical leadership needs. All engagements are a minimum of six months.

Popular

Associate

1 day per week

For organisations with defined, bounded clinical needs — governance, a specific regulatory workstream, or CQC preparation — that don't yet require a full CMO presence.

  • One structured working day per week
  • Board and leadership meeting attendance
  • Clinical governance framework ownership
  • Async email availability
  • Quarterly review and reporting
Enquire →
Popular

Strategic Advisor

4–6 days per month

Senior clinical advisory for organisations that need strategic input, investor or regulatory support, and a credible medical voice at board level — without operational clinical leadership.

  • 4–6 structured advisory days per month
  • Board-level clinical advisory input
  • Investor / fundraising support
  • Regulatory strategy review
  • Expert witness and medico-legal support
Enquire →

All engagements are structured as monthly retainers, billed in advance. Pricing is discussed openly during the discovery call — there are no hidden costs or variable billing.

When to Hire a Fractional Chief Medical Officer

These are the scenarios where a fractional CMO engagement delivers the most impact.

🚀
Digital Health / HealthTech

First CMO Hire for a Digital Health Scale-Up

A Series A digital health company needs clinical credibility for their NHS procurement bid and DCB0129 compliance. No in-house medic exists. They need a named Clinical Safety Officer and someone who can represent them in clinical discussions with NHS buyers.

✓ Outcome: DCB0129 documentation complete, NHS trust pilot approved within 5 months
🔬
MedTech & Diagnostics

UKCA Marking Clinical Evaluation for a MedTech SME

A diagnostics company needs to complete their Clinical Evaluation Report (CER) and post-market surveillance plan for UKCA marking. They lack in-house clinical expertise and need a senior clinician to own the process and liaise with their Notified Body.

✓ Outcome: CER completed and accepted, UKCA marking achieved within 8 months
🏥
Private Clinic Group

CQC Inspection Preparation for a Private Clinic Group

A group of aesthetic and cosmetic surgery clinics is preparing for a CQC inspection. Governance frameworks are incomplete, incident reporting is inconsistent, and there is no named Medical Director. An imminent CQC visit has heightened the urgency.

✓ Outcome: Governance framework implemented, CQC inspection passed with 'Good' rating
🧪
Biotech / Pharma

Pharmacovigilance Setup for an Early-Stage Biotech

A pre-Series B biotech company is approaching first-in-human studies. They need a pharmacovigilance system, a qualified safety officer function, and a medical affairs strategy ahead of their next funding round.

✓ Outcome: PV system live, QPPV appointed, Series B completed with clinical credibility secured
🤝
Corporate / Fundraising

Clinical Due Diligence Support for an Investor

A growth equity investor is conducting due diligence on a health technology acquisition. They need independent senior clinical input to assess clinical risk, regulatory status, and the credibility of the target's medical claims.

✓ Outcome: Clinical risk report delivered within 2 weeks, investment decision supported
🏠
Care Sector

Medical Director for a Care Home Group

A group of care homes is CQC-registered and requires a named Medical Director. Their previous medical lead retired and they need a qualified replacement who can provide governance oversight and clinical leadership across multiple sites.

✓ Outcome: Named Medical Director in place within 4 weeks, CQC re-registration supported

Start With a Free 30-Minute Discovery Call

No obligation. A confidential conversation to understand your clinical leadership needs and whether a fractional CMO engagement is the right fit.

  • 🩺Discuss your organisation's clinical leadership gaps and regulatory obligations
  • 📋Understand how the fractional CMO model works and whether it suits your stage
  • 💰Get a transparent indication of engagement scope and investment
  • 📅Choose a time that works for you — calls available mornings and evenings
  • 🔒Fully confidential — NDA available on request before the call
Book Your Discovery Call →

What to Prepare

The discovery call works best when you come prepared with:

  • A brief description of your organisation and what it does
  • Any current clinical or regulatory challenges you're facing
  • Whether you have any in-house clinical resource already
  • A rough sense of your timeline and urgency
  • Any questions about the fractional CMO model that you want answered

Calls are conducted via Zoom or Teams. A calendar invite with joining details is sent automatically on booking.

Send an Enquiry

Prefer to write first? Complete the form and we'll respond within one business day. All enquiries are treated with complete confidentiality.

🔒 Confidentiality Guarantee

Your details are kept strictly confidential and never shared with third parties. An NDA is available on request prior to any substantive discussion.

🔒 Your details are kept strictly confidential and never shared with third parties.

Enquiry Received

Thank you — we'll be in touch within one business day.
In the meantime, feel free to book a discovery call directly.

Frequently Asked Questions

What exactly is a Fractional Chief Medical Officer?
A Fractional Chief Medical Officer is a senior, board-level physician who provides medical and clinical leadership to your organisation on a part-time basis — typically one to two days per week. Rather than recruiting a full-time CMO (which can cost £200,000–£400,000 per year in salary and on-costs, plus a lengthy hiring process), you access the same calibre of senior clinical leadership scaled to the time and scope you actually need. The "fractional" refers to the fraction of working time dedicated to your organisation. Unlike a consultant who delivers a one-off piece of work, a fractional CMO is an ongoing member of your leadership team — attending board meetings, owning clinical workstreams, and building institutional knowledge over time.
How much does a Fractional CMO cost in the UK?
Fractional CMO engagements are structured as monthly retainers, typically representing a significant fraction of the cost of a full-time CMO hire. A full-time Chief Medical Officer at a UK healthcare organisation would typically command £200,000–£400,000 per year in salary plus pension, bonuses, and recruitment costs. A fractional CMO at one to two days per week starts from considerably less than this. Exact pricing depends on engagement level, scope, sector complexity, and whether specialist knowledge is required. All pricing is discussed openly and transparently during the discovery call — we provide a written proposal within 48 hours and there are no variable or hidden costs.
Who is this service designed for?
This service is built specifically for growing organisations that need senior clinical leadership but are not yet at the scale or stage to justify a full-time appointment. The ideal client typically has zero or one in-house medic, operates in a regulated or clinically complex space, and is either appointing their first medical leader or replacing one who has moved on. That typically means digital health companies, MedTech SMEs, early-stage biotech, private clinic groups, care providers, corporate health businesses, consumer health brands, and a range of other health-adjacent sectors.
Fractional CMO vs Interim CMO — what's the difference?
An interim CMO is typically a full-time temporary appointment — someone who steps into a CMO role for 3–12 months while you recruit a permanent replacement. They work exclusively for you, full-time, at a daily rate that typically makes them comparable in cost to a permanent hire. A fractional CMO, by contrast, works across multiple organisations simultaneously but is genuinely embedded in yours — they are a real ongoing member of your leadership team, not a project consultant. The fractional model is the right choice when you need continuous, embedded clinical leadership at a fraction of the cost. The interim model suits organisations that have had a CMO, need full-time cover during a transition, and have the budget to support it.
Why is there a minimum six-month engagement?
Meaningful clinical leadership cannot be delivered in one or two months. A fractional CMO needs time to understand your organisation, build trust with your team, assess your clinical risk landscape, and begin making a genuine difference. Short engagements also tend to produce short-term thinking — the kinds of governance and regulatory work that create lasting value require sustained attention. The minimum six months exists to ensure every engagement delivers real outcomes, not just advice on paper.
How does a remote engagement actually work?
All engagements are remote-first, structured around a regular weekly or fortnightly working rhythm. Depending on the engagement level, this includes dedicated working sessions (clinical governance reviews, regulatory work, strategy days), attendance at leadership and board meetings via video call, and availability for async questions between sessions. Agreed in-person attendance — such as board meetings, CQC preparation visits, or team away days — is built into the engagement terms from the start.
What industries and settings do you work with?
We work with a broad range of organisations where clinical or medical leadership is needed but often absent: digital health and HealthTech start-ups, MedTech and diagnostics SMEs, early-stage biotech and pharma, private clinic groups, care home and homecare providers, corporate and occupational health businesses, consumer health and nutrition brands, sports and aesthetics medicine, health insurance and insurtech products, and medico-legal practices.

Guides for Healthcare Founders & Leaders

In-depth articles on clinical governance, regulatory affairs, and medical leadership — written for the CEOs, founders, and board members of growing healthcare organisations.

Website Terms of Use

Last updated: April 2026  ·  CMOAdvisory

1. About This Website

This website is operated by CMOAdvisory ("we", "us", "our"). By accessing or using this website, you agree to be bound by these Website Terms of Use. If you do not agree, please do not use this website.

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The content published on this website — including articles, guides, service descriptions, and FAQs — is provided for general informational and educational purposes only. Nothing on this website constitutes:

All information is provided in good faith and is believed to be accurate at the date of publication, but no warranty is given as to its accuracy, completeness, or fitness for a particular purpose. Regulatory and legal requirements change frequently; you should always verify current requirements with the relevant regulatory body or qualified legal adviser.

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Terms of Business

Last updated: April 2026  ·  CMOAdvisory

1. Introduction

These Terms of Business govern the provision of clinical advisory, fractional Chief Medical Officer, and related services by CMOAdvisory ("we", "the CMO") to client organisations ("you", "the Client"). By entering into an engagement with CMOAdvisory, you agree to these terms. All engagements are also subject to a specific written Client Services Agreement which sets out the particular scope, term, and commercial arrangements of your engagement.

2. Services

CMOAdvisory provides senior clinical advisory and medical executive leadership services to organisations operating in healthcare, MedTech, digital health, life sciences, and related sectors. Services may include clinical governance, regulatory affairs support, patient safety, medical affairs strategy, digital health compliance, named medical director functions, medico-legal advisory, and board-level clinical representation.

Services are provided to organisations, not to individual patients. CMOAdvisory does not provide patient-facing clinical care.

3. Engagement Terms

All engagements commence with a formal written Client Services Agreement signed by both parties. No obligations arise until a signed agreement is in place. The minimum engagement term is six (6) months unless otherwise agreed in writing.

Engagements are structured as monthly retainers covering an agreed number of working days per week or per month. Retainers are billed in advance at the start of each calendar month. Day rates and retainer amounts are set out in the individual Client Services Agreement.

4. Payment Terms

Invoices are payable within 14 days of issue. Late payment may attract statutory interest under the Late Payment of Commercial Debts (Interest) Act 1998. CMOAdvisory reserves the right to suspend services where invoices remain unpaid beyond 30 days without prior agreement.

5. Confidentiality

CMOAdvisory treats all client information as strictly confidential. We do not disclose client identities or the nature of any engagement without prior written consent, except where required by law, a regulatory authority, or professional obligation. Clients are asked to treat our working methods, rates, and proprietary materials with equivalent confidentiality. A Mutual Non-Disclosure Agreement is available on request prior to any substantive discussions.

6. Independence and Conflicts of Interest

CMOAdvisory operates across multiple client organisations. We manage conflicts of interest through sector exclusivity provisions agreed in individual Client Services Agreements. We will not accept an engagement that creates a direct conflict with an existing client without the prior written consent of both parties.

7. Professional Indemnity

CMOAdvisory maintains appropriate professional indemnity insurance for the services provided. Details of current indemnity arrangements are available on request. Clients are responsible for ensuring their organisation has appropriate indemnity coverage for the clinical activities they conduct.

8. Limitation of Liability

CMOAdvisory's liability to any client is limited to the total fees paid in the twelve months immediately preceding the event giving rise to the claim, except in cases of death or personal injury caused by negligence, or fraud. CMOAdvisory is not liable for indirect, consequential, or incidental losses.

9. Termination

Either party may terminate an engagement at the end of any month by giving not less than 30 days' written notice, subject to any minimum term agreed in the Client Services Agreement. CMOAdvisory may terminate immediately in the event of material breach by the Client, including non-payment.

10. Governing Law

These Terms of Business and all client engagements are governed by the laws of England and Wales. Any disputes are subject to the exclusive jurisdiction of the courts of England and Wales.

11. Contact

Questions about these terms: hello@chiefmedicalofficer.co.uk

Privacy Policy

Last updated: April 2026  ·  CMOAdvisory

1. Who We Are

CMOAdvisory ("we", "us", "our") is a clinical advisory practice providing fractional Chief Medical Officer and related services. For the purposes of UK data protection law (UK GDPR and the Data Protection Act 2018), we are the data controller for personal data collected via this website. You can contact us at: hello@chiefmedicalofficer.co.uk

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